pilot study on the genetic vary of Mycobacterium tuberculosis difficult strains from tuberculosis victims

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Melting dsDNA Donor Molecules Vastly Improves Precision Genome Enhancing in Caenorhabditiselegans

 

CRISPR genome modifying has revolutionized genetics in numerous organisms. Inside the nematode Caenorhabditiselegans one injection into each of the two gonad arms of an grownup hermaphrodite exposes tons of of meiotic germ cells to modifying mixtures, permitting the restoration of a lot of indels or small precision edits from each effectively injected animal. Sadly, considerably for prolonged insertions, modifying efficiencies can differ broadly, necessitating a lot of injections, and generally requiring co-selection strategies.

 

Proper right here we current that melting double stranded DNA (dsDNA) donor molecules earlier to injection will improve the frequency of tangible homology-directed restore (HDR) by a lot of fold for longer edits. We describe troubleshooting strategies that permit persistently extreme modifying efficiencies ensuing, as an illustration, in as a lot as 100 unbiased GFP knock-ins from a single injected animal. These efficiencies make C. elegans by far the best metazoan to genome edit, eradicating limitations to the use and adoption of this facile system as a model for understanding animal biology.

 

 

 

Water-Pipe Smoking Publicity Deregulates a Set of Genes Associated to Human Head and Neck Most cancers Development and Prognosis

 

  • Water-pipe smoking (WPS) is popping into probably the most well-liked sort of tobacco use among the many many youth, notably inside the Heart East, altering cigarettes rapidly and turning into a critical risk of tobacco dependancy worldwide. Smoke from WPS accommodates comparable toxins as these present in cigarette smoke and is linked immediately with a number of kinds of cancers along with lung and head and neck (HN) carcinomas.

 

  • Nonetheless, the underlying molecular pathways and/or purpose genes accountable for the carcinogenic course of are nonetheless unknown. On this study, human common oral epithelial (HNOE) cells, NanoStringPanCancer Pathways panel of 770 gene transcripts and quantitative real-time polymerase chain response (qRT-PCR) analysis had been utilized to seek out differentially expressed genes (DEG) modulated by WPS. In silico analysis was carried out to research the affect of these genes in HN most cancers affected particular person’s biology and consequence. We found that WPS can induce the epithelial-mesenchymal transition (EMT: hallmark of most cancers growth) of HNOE cells.

 

  • Further significantly, our analysis of NanoString revealed 23 genes deregulated beneath the affect of WPS, accountable for the modulation of cell cycle, proliferation, migration/invasion, apoptosis, signal transduction, and inflammatory response. Extra analysis was carried out using qRT-PCR of HNOE WPS-exposed and unexposed cells supported the reliability of our NanoString info.

 

  • Moreover, we exhibit these DEG to be upregulated in most cancers in distinction with common tissue. Using the Kaplan-Meier analysis, we seen a significant affiliation between WPS-deregulated genes and relapse-free survival/complete survival in HN most cancers victims. Our findings point out that WPS can modulate EMT along with a set of genes which could be immediately involved in human HN carcinogenesis, thereby affecting HN most cancers victims’ survival.

 

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Vav 1 Oncogene (VAV1) Polyclonal Antibody

MBS2032848-02mL 0.2mL
EUR 220

Vav 1 Oncogene (VAV1) Polyclonal Antibody

MBS2032848-05mL 0.5mL
EUR 365

Vav 1 Oncogene (VAV1) Polyclonal Antibody

MBS2032848-1mL 1mL
EUR 445

Vav 1 Oncogene (VAV1) Polyclonal Antibody

MBS2032848-5mL 5mL
EUR 1220

Polyclonal Antibody to Vav 1 Oncogene (VAV1)

PAC213Hu01 100ul
EUR 245
  • Rabbit

Polyclonal Antibody to Vav 1 Oncogene (VAV1)

PAC213Mu01 100ul
EUR 252
  • Rabbit

Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2027967-01mL 0.1mL
EUR 175

Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2027967-02mL 0.2mL
EUR 220

Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2027967-05mL 0.5mL
EUR 355

Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2027967-1mL 1mL
EUR 435

Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2027967-5mL 5mL
EUR 1185

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Human)

4-PAC213Hu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Leu426~Arg696)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Vav 1 Oncogene (VAV1)

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Mouse)

4-PAC213Mu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Gly565~Ala795)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Vav 1 Oncogene (VAV1)

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Human), PE

4-PAC213Hu01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Leu426~Arg696)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Vav 1 Oncogene (VAV1). This antibody is labeled with PE.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Mouse), PE

4-PAC213Mu01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Gly565~Ala795)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Vav 1 Oncogene (VAV1). This antibody is labeled with PE.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Human), APC

4-PAC213Hu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Leu426~Arg696)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Vav 1 Oncogene (VAV1). This antibody is labeled with APC.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Human), Cy3

4-PAC213Hu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Leu426~Arg696)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Vav 1 Oncogene (VAV1). This antibody is labeled with Cy3.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Human), HRP

4-PAC213Hu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Leu426~Arg696)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Vav 1 Oncogene (VAV1). This antibody is labeled with HRP.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Mouse), APC

4-PAC213Mu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Gly565~Ala795)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Vav 1 Oncogene (VAV1). This antibody is labeled with APC.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Mouse), Cy3

4-PAC213Mu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Gly565~Ala795)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Vav 1 Oncogene (VAV1). This antibody is labeled with Cy3.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Mouse), HRP

4-PAC213Mu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Gly565~Ala795)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Vav 1 Oncogene (VAV1). This antibody is labeled with HRP.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Human), FITC

4-PAC213Hu01-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Leu426~Arg696)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Vav 1 Oncogene (VAV1). This antibody is labeled with FITC.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Mouse), FITC

4-PAC213Mu01-FITC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Gly565~Ala795)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Vav 1 Oncogene (VAV1). This antibody is labeled with FITC.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Human), Biotinylated

4-PAC213Hu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Leu426~Arg696)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Vav 1 Oncogene (VAV1). This antibody is labeled with Biotin.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Mouse), Biotinylated

4-PAC213Mu01-Biotin
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Gly565~Ala795)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Vav 1 Oncogene (VAV1). This antibody is labeled with Biotin.

PE-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064027-01mL 0.1mL
EUR 265

PE-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064027-02mL 0.2mL
EUR 355

PE-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064027-05mL 0.5mL
EUR 660

PE-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064027-1mL 1mL
EUR 810

PE-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064027-5mL 5mL
EUR 2330

PE-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064033-01mL 0.1mL
EUR 275

PE-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064033-02mL 0.2mL
EUR 365

PE-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064033-05mL 0.5mL
EUR 675

PE-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064033-1mL 1mL
EUR 835

PE-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064033-5mL 5mL
EUR 2395

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Human), APC-Cy7

4-PAC213Hu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Leu426~Arg696)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Vav 1 Oncogene (VAV1). This antibody is labeled with APC-Cy7.

Vav 1 Oncogene (VAV1) Polyclonal Antibody (Mouse), APC-Cy7

4-PAC213Mu01-APC-Cy7
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: VAV1 (Gly565~Ala795)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Vav 1 Oncogene (VAV1). This antibody is labeled with APC-Cy7.

APC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064028-01mL 0.1mL
EUR 265

APC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064028-02mL 0.2mL
EUR 355

APC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064028-05mL 0.5mL
EUR 660

APC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064028-1mL 1mL
EUR 810

APC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064028-5mL 5mL
EUR 2330

Cy3-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064029-01mL 0.1mL
EUR 265

Cy3-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064029-02mL 0.2mL
EUR 355

Cy3-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064029-05mL 0.5mL
EUR 660

Cy3-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064029-1mL 1mL
EUR 810

Cy3-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064029-5mL 5mL
EUR 2330

HRP-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064031-01mL 0.1mL
EUR 205

HRP-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064031-02mL 0.2mL
EUR 255

HRP-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064031-05mL 0.5mL
EUR 450

HRP-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064031-1mL 1mL
EUR 545

HRP-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064031-5mL 5mL
EUR 1530

APC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064034-01mL 0.1mL
EUR 275

APC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064034-02mL 0.2mL
EUR 365

APC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064034-05mL 0.5mL
EUR 675

APC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064034-1mL 1mL
EUR 835

APC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064034-5mL 5mL
EUR 2395

Cy3-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064035-01mL 0.1mL
EUR 275

Cy3-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064035-02mL 0.2mL
EUR 365

Cy3-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064035-05mL 0.5mL
EUR 675

Cy3-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064035-1mL 1mL
EUR 835

Cy3-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064035-5mL 5mL
EUR 2395

HRP-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064037-01mL 0.1mL
EUR 205

HRP-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064037-02mL 0.2mL
EUR 260

HRP-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064037-05mL 0.5mL
EUR 460

HRP-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064037-1mL 1mL
EUR 560

HRP-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064037-5mL 5mL
EUR 1570

FITC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064030-01mL 0.1mL
EUR 215

FITC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064030-02mL 0.2mL
EUR 265

FITC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064030-05mL 0.5mL
EUR 480

FITC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064030-1mL 1mL
EUR 585

FITC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064030-5mL 5mL
EUR 1645

FITC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064036-01mL 0.1mL
EUR 220

FITC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064036-02mL 0.2mL
EUR 275

FITC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064036-05mL 0.5mL
EUR 490

FITC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064036-1mL 1mL
EUR 600

FITC-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064036-5mL 5mL
EUR 1690

Biotin-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2094291-01mL 0.1mL
EUR 185

Biotin-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2094291-02mL 0.2mL
EUR 230

Biotin-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2094291-05mL 0.5mL
EUR 385

Biotin-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2094291-1mL 1mL
EUR 470

Biotin-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2094291-5mL 5mL
EUR 1300

Biotin-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2094292-01mL 0.1mL
EUR 190

Biotin-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2094292-02mL 0.2mL
EUR 230

Biotin-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2094292-05mL 0.5mL
EUR 395

Biotin-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2094292-1mL 1mL
EUR 485

Biotin-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2094292-5mL 5mL
EUR 1335

APC/CY7-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064026-1mL 1mL
EUR 1185

APC/CY7-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064026-5mL 5mL
EUR 3445

APC/CY7-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064026-5x5mL 5x5mL
EUR 15495

APC/CY7-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064032-1mL 1mL
EUR 1220

APC/CY7-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064032-5mL 5mL
EUR 3540

APC/CY7-Linked Polyclonal Antibody to Vav 1 Oncogene (VAV1)

MBS2064032-5x5mL 5x5mL
EUR 15930

Vav 1 Oncogene (VAV1) Antibody

20-abx128450
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  • Ask for price
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Vav 1 Oncogene (VAV1) Antibody

20-abx131502
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Vav 1 Oncogene (VAV1) Antibody

abx332110-100ul 100 ul
EUR 510
  • Shipped within 5-10 working days.

Vav 1 Oncogene (VAV1) Antibody

20-abx327434
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  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Vav 1 Oncogene (VAV1) Antibody

20-abx327966
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  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Vav 1 Oncogene (VAV1) Antibody

20-abx329103
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  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Vav 1 Oncogene (VAV1) Antibody

abx331549-100ul 100 ul
EUR 510
  • Shipped within 5-10 working days.

Vav 1 Oncogene (VAV1) Antibody

abx327434-100g 100 µg
EUR 250

Vav 1 Oncogene (VAV1) Antibody

abx327434-50g 50 µg
EUR 187.5

Vav 1 Oncogene (VAV1) Antibody

abx327966-100g 100 µg
EUR 250

Vav 1 Oncogene (VAV1) Antibody

abx327966-50g 50 µg
EUR 187.5

Vav 1 Oncogene (VAV1) Antibody

abx329103-100l 100 µl
EUR 187.5

Vav 3 Oncogene (VAV3) Polyclonal Antibody

CAU22609-100ul 100ul
EUR 235.2

Vav 3 Oncogene (VAV3) Polyclonal Antibody

CAU22609-200ul 200ul
EUR 294

Vav 3 Oncogene (VAV3) Polyclonal Antibody

CAU22610-100ul 100ul
EUR 235.2

Vav 3 Oncogene (VAV3) Polyclonal Antibody

CAU22610-200ul 200ul
EUR 294

Polyclonal Antibody to Vav 3 Oncogene (VAV3)

PAE929Hu01 100ul
EUR 245
  • Rabbit

 

 

A pilot study on the genetic vary of Mycobacterium tuberculosis difficult strains from tuberculosis victims inside the Littoral space of Cameroon

Background: The re-emergence of tuberculosis (TB) worldwide, compounded by multi-drug resistance (MDR) of the causative brokers constitutes a significant issue to the administration of the sickness. Speedy evaluation and proper stress identification are pivotal to the administration of the sickness. This pilot study investigated the genetic vary of Mycobacterium tuberculosis difficult (MTBC) strains from TB victims inside the Littoral space of Cameroon along with their resistance to rifampicin (RIF).

 

Victims and techniques: This was a cross sectional hospital-based study carried out between January and December 2017 and along with 158 isolates from sputum smear constructive folks [105 (66.5%) males and 53 (33.5%) females]. Sputum samples had been examined using Xpert MTB/RIF, adopted by custom on Lowenstein-Jensen medium. Isolates had been further subjected to molecular characterization using IS6110 typing, deletion analysis and spoligotyping.

 

Outcomes: 13 (8.8%) of the 147 isolates with susceptibility outcomes accessible had been proof towards RIF. Drug resistance occurred in 5/50 (10%) female compared with 8/97 (8.2%) male (OR, 0.81; 0.25-2.62; p = 0.764), and there was no very important distinction all through the age ranges (p = 0.448). Nonetheless, RIF resistance was associated (OR, 0.18, 95%CI, 0.05-0.69; p = 0.023) with beforehand dealt with victims [(4/14 (28.6%)] compared with new ones [9/133 (6.8%)].

The 150 acknowledged lineages included amongst others 54 (36%) Cameroon, 18 (12%) UgandaI, 32 (21.3%) Haarlem, 17 (11.3%) Ghana, 9(6%) West African 1, 7(4.7%) Delhi/CAS, 4 (2.7%) LAM and three (2%) UgandaII. Of the 150 isolates, a very powerful cluster was the Cameroon SIT 61, with 43(28.7%) isolates. Six (35.3%) of the 17 UgandaI sub-lineage had been RIF resistant (OR, 9.58; 95%CI, 2.74-33.55, p = 0.001).

 

Conclusion: The cosmopolitan Littoral space presents with a big Mycobacterium tuberculosis (MTB) strains vary and the UgandaI sub-lineage attainable associated to RIF resistance. Understanding the unfold of this clade by means of surveillance will enhance TB administration inside the space.

 

Pim-1 Oncogene (PIM1) Polyclonal Antibody
CAU24102-200ul 200ul
EUR 294
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
PAC578Hu01 100ul
EUR 245
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Polyclonal Antibody to Pim-1 Oncogene (PIM1)
PAC578Mu01 100ul
EUR 252
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Polyclonal Antibody to Pim-1 Oncogene (PIM1)
PAC578Ra01 100ul
EUR 266
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Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2002188-01mL 0.1mL
EUR 175
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2002188-02mL 0.2mL
EUR 220
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2002188-05mL 0.5mL
EUR 355
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2002188-1mL 1mL
EUR 435
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2002188-5mL 5mL
EUR 1185
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2002793-01mL 0.1mL
EUR 175
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2002793-02mL 0.2mL
EUR 220
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2002793-05mL 0.5mL
EUR 365
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2002793-1mL 1mL
EUR 445
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2002793-5mL 5mL
EUR 1220
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2004826-01mL 0.1mL
EUR 180
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2004826-02mL 0.2mL
EUR 225
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2004826-05mL 0.5mL
EUR 380
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2004826-1mL 1mL
EUR 465
Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2004826-5mL 5mL
EUR 1285
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat)
4-PAC578Ra01
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  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1)
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse)
4-PAC578Mu01
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  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1)
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), PE
4-PAC578Ra01-PE
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  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with PE.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), APC
4-PAC578Ra01-APC
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  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), Cy3
4-PAC578Ra01-Cy3
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  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Cy3.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), HRP
4-PAC578Ra01-HRP
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  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with HRP.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), PE
4-PAC578Mu01-PE
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  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with PE.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), FITC
4-PAC578Ra01-FITC
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  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with FITC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), APC
4-PAC578Mu01-APC
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  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with APC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), Cy3
4-PAC578Mu01-Cy3
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  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with Cy3.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), HRP
4-PAC578Mu01-HRP
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  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with HRP.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), FITC
4-PAC578Mu01-FITC
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  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with FITC.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), Biotinylated
4-PAC578Ra01-Biotin
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  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with Biotin.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), Biotinylated
4-PAC578Mu01-Biotin
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  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with Biotin.
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Rat), APC-Cy7
4-PAC578Ra01-APC-Cy7
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  • Sequence of the immunogen: PIM1 (Tyr38~Leu177)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Rat Pim-1 Oncogene (PIM1). This antibody is labeled with APC-Cy7.
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066795-01mL 0.1mL
EUR 265
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066795-02mL 0.2mL
EUR 355
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066795-05mL 0.5mL
EUR 660
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066795-1mL 1mL
EUR 810
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066795-5mL 5mL
EUR 2330
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066801-01mL 0.1mL
EUR 275
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066801-02mL 0.2mL
EUR 365
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066801-05mL 0.5mL
EUR 675
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066801-1mL 1mL
EUR 835
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066801-5mL 5mL
EUR 2395
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066807-01mL 0.1mL
EUR 285
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066807-02mL 0.2mL
EUR 380
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066807-05mL 0.5mL
EUR 710
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066807-1mL 1mL
EUR 875
PE-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066807-5mL 5mL
EUR 2525
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Human, Mouse, Rat)
4-PAC578Hu01
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  • Sequence of the immunogen: PIM1 (Tyr129~Leu268)
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Human, Mouse, Rat Pim-1 Oncogene (PIM1)
Pim-1 Oncogene (PIM1) Polyclonal Antibody (Mouse), APC-Cy7
4-PAC578Mu01-APC-Cy7
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  • 100ul
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  • Sequence of the immunogen: PIM1 (Tyr122~Leu261)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Pim-1 Oncogene (PIM1). This antibody is labeled with APC-Cy7.
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066796-01mL 0.1mL
EUR 265
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066796-02mL 0.2mL
EUR 355
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066796-05mL 0.5mL
EUR 660
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066796-1mL 1mL
EUR 810
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066796-5mL 5mL
EUR 2330
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066797-01mL 0.1mL
EUR 265
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066797-02mL 0.2mL
EUR 355
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066797-05mL 0.5mL
EUR 660
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066797-1mL 1mL
EUR 810
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066797-5mL 5mL
EUR 2330
HRP-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066799-01mL 0.1mL
EUR 205
HRP-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066799-02mL 0.2mL
EUR 255
HRP-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066799-05mL 0.5mL
EUR 450
HRP-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066799-1mL 1mL
EUR 545
HRP-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066799-5mL 5mL
EUR 1530
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066802-01mL 0.1mL
EUR 275
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066802-02mL 0.2mL
EUR 365
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066802-05mL 0.5mL
EUR 675
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066802-1mL 1mL
EUR 835
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066802-5mL 5mL
EUR 2395
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066803-01mL 0.1mL
EUR 275
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066803-02mL 0.2mL
EUR 365
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066803-05mL 0.5mL
EUR 675
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066803-1mL 1mL
EUR 835
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066803-5mL 5mL
EUR 2395
HRP-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066805-01mL 0.1mL
EUR 205
HRP-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066805-02mL 0.2mL
EUR 260
HRP-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066805-05mL 0.5mL
EUR 460
HRP-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066805-1mL 1mL
EUR 560
HRP-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066805-5mL 5mL
EUR 1570
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066808-01mL 0.1mL
EUR 285
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066808-02mL 0.2mL
EUR 380
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066808-05mL 0.5mL
EUR 710
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066808-1mL 1mL
EUR 875
APC-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066808-5mL 5mL
EUR 2525
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066809-01mL 0.1mL
EUR 285
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066809-02mL 0.2mL
EUR 380
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066809-05mL 0.5mL
EUR 710
Cy3-Linked Polyclonal Antibody to Pim-1 Oncogene (PIM1)
MBS2066809-1mL 1mL
EUR 875

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