
The Genetic Diversification of a Single Bluetongue Virus Strain Using an In Vitro Model of Alternating-Host Transmission
Bluetongue virus (BTV) is an arbovirus that has been associated to dramatic epizootics in every wild and residential ruminants in newest a very long time. As a segmented, double-stranded RNA virus, BTV can evolve by a lot of mechanisms due to its genomic building. Nonetheless, the affect of BTV’s alternating-host transmission cycle on the virus’s genetic diversification stays poorly understood. Complete genome sequencing approaches provide a platform for investigating the affect of host-alternation all through all ten segments of BTV’s genome.
To understand the operate of alternating hosts in BTV’s genetic diversification, a topic isolate was passaged beneath three utterly totally different conditions: (i) serial passages in Culicoidessonorensis cells, (ii) serial passages in bovine pulmonary artery endothelial cells, or (iii) alternating passages between insect and bovine cells.
Aliquots of virus had been sequenced, and single nucleotide variants had been acknowledged. Measures of viral inhabitants genetics had been used to quantify the genetic diversification that occurred. Two consensus variants in segments 5 and 10 occurred in virus from all three conditions.
Whereas variants arose all through all passages, measures of genetic vary remained largely comparable all through cell custom conditions. No matter passage in a relaxed in vitro system, we found that this BTV isolate exhibited genetic stability all through passages and conditions. Our findings underscore the dear operate that full genome sequencing may play in enhancing understanding of viral evolution and highlight the genetic stability of BTV.
Novel Gene Rearrangement and the Full Mitochondrial Genome of Cynoglossusmonopus: Insights into the Envolution of the Family Cynoglossidae (Pleuronectiformes)
Cynoglossusmonopus, a small benthic fish, belongs to the Cynoglossidae, Pleuronectiformes. It was not usually studied due to its low abundance and cryptical life-style. With the intention to understand the mitochondrial genome and the phylogeny in Cynoglossidae, all the mitogenome of C. monopus has been sequenced and analyzed for the first time. The whole dimension is 16,425 bp, generally containing 37 genes with novel gene rearrangements. The tRNA-Gln gene is inverted from the sunshine to the heavy strand and translocated from the downstream of tRNA-Ile gene to its upstream. The administration space (CR) translocated downstream to the three’-end of ND1 gene adjoining to inverted to tRNA-Gln and left a 24 bp trace fragment inside the genuine place.
The phylogenetic timber had been reconstructed by Bayesian inference (BI) and most probability (ML) methods based mostly totally on the mitogenomic info of 32 tonguefish species and two outgroups. The outcomes assist the idea that Cynoglossidae is a monophyletic group and level out that C. monopus has the closest phylogenetic relationship with C. puncticeps.
By combining fossil info and mitogenome info, the time-calibrated evolutionary tree of households Cynoglossidae and Soleidae was firstly provided, and it was indicated that Cynoglossidae and Soleidae had been differentiated from each other all through Paleogene, and the evolutionary strategy of family Cynoglossidae coated the Quaternary, Neogene and Paleogene durations.

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CN-04610H1 | ChemNorm | 96T | EUR 530.4 |
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CN-04610H2 | ChemNorm | 48T | EUR 351.6 |
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GA-E1696HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
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GA-E1696HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
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QY-E01682 | Qayee Biotechnology | 96T | EUR 433.2 |
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YLA2715HU-48T | Shanghai YL Biotech | 48T | EUR 435 |
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YLA2715HU-96T | Shanghai YL Biotech | 96T | EUR 562.5 |
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STJ16100363 | St John's Laboratory | 1 mL | EUR 1041.6 |
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10R-E126A | Fitzgerald | 50 ug | EUR 501.6 |
Description: Mouse monoclonal Epithelium Specific Antigen antibody |
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abx232799-100ug | Abbexa | 100 ug | EUR 610.8 |
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20-abx214622 | Abbexa |
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abx224065-100ug | Abbexa | 100 ug | EUR 493.2 |
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20-abx172278 | Abbexa |
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20-abx327226 | Abbexa |
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20-abx324346 | Abbexa |
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abx011925-100ul | Abbexa | 100 ul | EUR 493.2 |
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abx037446-100ug | Abbexa | 100 ug | EUR 469.2 |
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abx037447-100ug | Abbexa | 100 ug | EUR 469.2 |
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20-abx104775 | Abbexa |
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abx430513-200ul | Abbexa | 200 ul | EUR 460.8 |
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20-abx112318 | Abbexa |
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20-abx176308 | Abbexa |
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20-abx125330 | Abbexa |
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20-abx242428 | Abbexa |
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20-abx242433 | Abbexa |
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20-abx123431 | Abbexa |
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20-abx129957 | Abbexa |
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abx159488-100ul | Abbexa | 100 ul | EUR 560.4 |
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20-abx270202 | Abbexa |
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abx030033-400ul | Abbexa | 400 ul | EUR 627.6 |
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abx030033-80l | Abbexa | 80 µl | EUR 343.2 |
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20-abx338680 | Abbexa |
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abx331190-100ul | Abbexa | 100 ul | EUR 510 |
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BNC432041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF543 conjugate, Concentration: 0.1mg/mL |
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BNC432041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF543 conjugate, Concentration: 0.1mg/mL |
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BNC402041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF640R conjugate, Concentration: 0.1mg/mL |
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BNC402041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF640R conjugate, Concentration: 0.1mg/mL |
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BNC052041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405M conjugate, Concentration: 0.1mg/mL |
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BNC052041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405M conjugate, Concentration: 0.1mg/mL |
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BNC472041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF647 conjugate, Concentration: 0.1mg/mL |
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BNC472041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF647 conjugate, Concentration: 0.1mg/mL |
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BNC802041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680 conjugate, Concentration: 0.1mg/mL |
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BNC802041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680 conjugate, Concentration: 0.1mg/mL |
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BNC612041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF660R conjugate, Concentration: 0.1mg/mL |
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BNC612041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF660R conjugate, Concentration: 0.1mg/mL |
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BNC552041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF555 conjugate, Concentration: 0.1mg/mL |
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BNC552041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF555 conjugate, Concentration: 0.1mg/mL |
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BNUB2041-100 | Biotium | 100uL | EUR 316.8 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Concentration: 0.2mg/mL |
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BNUB2041-50 | Biotium | 50uL | EUR 486 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), 1mg/mL |
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BNUB2041-500 | Biotium | 500uL | EUR 615.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Concentration: 0.2mg/mL |
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BNCH2041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
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BNCH2041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL |
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BNC942041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF594 conjugate, Concentration: 0.1mg/mL |
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BNC942041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF594 conjugate, Concentration: 0.1mg/mL |
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BNCAP2041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
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BNCAP2041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL |
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BNCA2041-250 | Biotium | 250uL | EUR 472.8 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), APC conjugate, Concentration: 0.1mg/mL |
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BNC882041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF488A conjugate, Concentration: 0.1mg/mL |
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BNC882041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF488A conjugate, Concentration: 0.1mg/mL |
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BNCB2041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Biotin conjugate, Concentration: 0.1mg/mL |
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BNCB2041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), Biotin conjugate, Concentration: 0.1mg/mL |
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BNC042041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405S conjugate, Concentration: 0.1mg/mL |
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BNC042041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF405S conjugate, Concentration: 0.1mg/mL |
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BNC702041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF770 conjugate, Concentration: 0.1mg/mL |
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BNC702041-500 | Biotium | 500uL | EUR 654 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF770 conjugate, Concentration: 0.1mg/mL |
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BNC812041-100 | Biotium | 100uL | EUR 279.6 |
Description: Primary antibody against EpCAM / CD326 (Epithelial Marker) (EGP40/2041R), CF680R conjugate, Concentration: 0.1mg/mL |
Genome-Broad Identification and Characterization of the SHI-Related Sequence Gene Family in Rice
Rice (Oryzasativa) yield is correlated to various parts. Transcription regulators are important parts, akin to the on a regular basis SHORT INTERNODES-related sequences (SRSs), which encode proteins with single zinc finger motifs. Nonetheless, info regarding the evolutionary and sensible traits of the SRS gene family members in rice is insufficient.
Subsequently, we carried out a genome-wide screening and characterization of the OsSRS gene family in Oryzasativa japonica rice. We moreover examined the SRS proteins from 11 rice sub-species, consisting of three cultivars, 6 wild varieties, and a few totally different genome kinds. SRS members from maize, sorghum, Brachypodiumdistachyon, and Arabidopsis had been moreover investigated.
All these SRS proteins exhibited species-specific traits, along with monocot- and dicot-specific traits, as assessed by phylogenetic analysis, which was further validated by gene building and motif analyses. Genome comparisons revealed that segmental duplications may need carried out very important roles inside the recombination of the OsSRS gene family and their expression ranges. The family was primarily subjected to purifying selective stress.
In addition to, the expression info demonstrated the distinct responses of OsSRS genes to various abiotic stresses and hormonal cures, indicating their sensible divergence. Our study provides a wonderful reference for elucidating the options of SRS genes in rice.
![]() PP2 (Src kinase inhibitor) |
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SIH-470-25MG | Stressmarq | 25 mg | EUR 884.4 |
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Description: The substance PP2 is a src kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is off-white solid which is soluble in DMSO (25 mg/ml). |
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SIH-470-5MG | Stressmarq | 5 mg | EUR 279.6 |
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Description: The substance PP2 is a src kinase inhibitor. It is synthetically produced and has a purity of ?98%. The pure substance is off-white solid which is soluble in DMSO (25 mg/ml). |
![]() SRC kinase signaling inhibitor 1 (SRCIN1) Antibody |
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abx331175-100ul | Abbexa | 100 ul | EUR 510 |
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![]() SRC kinase signaling inhibitor 1 (SRCIN1) Antibody |
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20-abx327632 | Abbexa |
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![]() Rat SRC kinase signaling inhibitor 1 (SRCIN1) ELISA Kit |
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abx392007-96tests | Abbexa | 96 tests | EUR 1093.2 |
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![]() Mouse SRC kinase signaling inhibitor 1 (SRCIN1) ELISA Kit |
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abx390644-96tests | Abbexa | 96 tests | EUR 1093.2 |
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![]() Human SRC kinase signaling inhibitor 1 (SRCIN1) ELISA Kit |
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abx385443-96tests | Abbexa | 96 tests | EUR 1093.2 |
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![]() Mouse SRC kinase signaling inhibitor 1, Srcin1 ELISA KIT |
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ELI-18126m | Lifescience Market | 96 Tests | EUR 1038 |
![]() Human SRC kinase signaling inhibitor 1, SRCIN1 ELISA KIT |
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ELI-13954h | Lifescience Market | 96 Tests | EUR 988.8 |
![]() Srcin1 ELISA Kit| Mouse SRC kinase signaling inhibitor 1 ELISA |
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EF016287 | Lifescience Market | 96 Tests | EUR 826.8 |
![]() Srcin1 ELISA Kit| Rat SRC kinase signaling inhibitor 1 ELISA Ki |
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EF019367 | Lifescience Market | 96 Tests | EUR 826.8 |
![]() Antizyme Inhibitor 1 (Antizyme inhibitor 1) Antibody |
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abx230450-100ug | Abbexa | 100 ug | EUR 577.2 |
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20-abx111016 | Abbexa |
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HY-101275 | MedChemExpress | 5mg | EUR 680.4 |
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HY-103663 | MedChemExpress | 10mM/1mL | EUR 207.6 |
![]() Cot inhibitor-1 |
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HY-32015 | MedChemExpress | 10mg | EUR 670.8 |
![]() DAAO inhibitor-1 |
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HY-111412 | MedChemExpress | 10mM/1mL | EUR 392.4 |
![]() CNT2 inhibitor-1 |
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HY-112843 | MedChemExpress | 25mg | EUR 2469.6 |
![]() mTOR inhibitor-1 |
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HY-112914 | MedChemExpress | 10mg | EUR 680.4 |
![]() Grp94 Inhibitor-1 |
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HY-112910 | MedChemExpress | 50mg | EUR 391.2 |
![]() Kinase inhibitor-1 |
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HY-43533 | MedChemExpress | 5mg | EUR 680.4 |
![]() IDO inhibitor 1 |
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B8310-100 | ApexBio | 100 mg | EUR 1173.6 |
![]() IDO inhibitor 1 |
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B8310-25 | ApexBio | 25 mg | EUR 547.2 |
![]() IDO inhibitor 1 |
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B8310-5 | ApexBio | 5 mg | EUR 212.4 |
![]() IDO inhibitor 1 |
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A3483-10 | ApexBio | 10 mg | EUR 553.2 |
Description: IDO inhibitor 1 is a potent and novel indoleamine-2,3 dioxygenase (IDO) inhibitor with IC50 value <100 nM. IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine and permits tumor cells to escape the immune system. |
![]() IDO inhibitor 1 |
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A3483-25 | ApexBio | 25 mg | EUR 774 |
Description: IDO inhibitor 1 is a potent and novel indoleamine-2,3 dioxygenase (IDO) inhibitor with IC50 value <100 nM. IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine and permits tumor cells to escape the immune system. |
![]() IDO inhibitor 1 |
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A3483-5 | ApexBio | 5 mg | EUR 382.8 |
Description: IDO inhibitor 1 is a potent and novel indoleamine-2,3 dioxygenase (IDO) inhibitor with IC50 value <100 nM. IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine and permits tumor cells to escape the immune system. |
![]() IDO inhibitor 1 |
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A3483-50 | ApexBio | 50 mg | EUR 1230 |
Description: IDO inhibitor 1 is a potent and novel indoleamine-2,3 dioxygenase (IDO) inhibitor with IC50 value <100 nM. IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine and permits tumor cells to escape the immune system. |
![]() ALK inhibitor 1 |
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HY-15357 | MedChemExpress | 50mg | EUR 1712.4 |
![]() Btk inhibitor 1 |
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HY-13036 | MedChemExpress | 50mg | EUR 2539.2 |
![]() IRAK inhibitor 1 |
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A3500-10 | ApexBio | 10 mg | EUR 529.2 |
Description: IC50: 35 nM for IRAK-4The interleukin-1 receptor associated kinase (IRAK) family is comprised of four family members IRAK-1, IRAK-2, IRAK-3/M, and IRAK-4. |
![]() IRAK inhibitor 1 |
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A3500-5 | ApexBio | 5 mg | EUR 404.4 |
Description: IC50: 35 nM for IRAK-4The interleukin-1 receptor associated kinase (IRAK) family is comprised of four family members IRAK-1, IRAK-2, IRAK-3/M, and IRAK-4. |
![]() IRAK inhibitor 1 |
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A3500-50 | ApexBio | 50 mg | EUR 1280.4 |
Description: IC50: 35 nM for IRAK-4The interleukin-1 receptor associated kinase (IRAK) family is comprised of four family members IRAK-1, IRAK-2, IRAK-3/M, and IRAK-4. |
![]() FAAH inhibitor 1 |
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HY-10862 | MedChemExpress | 5mg | EUR 392.4 |
![]() CCR6 inhibitor 1 |
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HY-112701 | MedChemExpress | 10mg | EUR 1093.2 |
![]() p38α inhibitor 1 |
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HY-114423 | MedChemExpress | 5mg | EUR 267.6 |
![]() IRAK inhibitor 1 |
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HY-13275 | MedChemExpress | 10mM/1mL | EUR 500.4 |
![]() HPGDS inhibitor 1 |
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B1046-1 | ApexBio | 1 mg | EUR 217.2 |
Description: HPGDS inhibitor 1 is an oral potent and selective inhibitor of hematopoietic prostaglandin D synthase (HPGDS) with IC50 value of 0.7nM [1].Prostaglandin D2 (PGD2) is a mediator of allergy and inflammation. |
![]() HPGDS inhibitor 1 |
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B1046-10 | ApexBio | 10 mg | EUR 774 |
Description: HPGDS inhibitor 1 is an oral potent and selective inhibitor of hematopoietic prostaglandin D synthase (HPGDS) with IC50 value of 0.7nM [1].Prostaglandin D2 (PGD2) is a mediator of allergy and inflammation. |
![]() HPGDS inhibitor 1 |
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B1046-5 | ApexBio | 5 mg | EUR 456 |
Description: HPGDS inhibitor 1 is an oral potent and selective inhibitor of hematopoietic prostaglandin D synthase (HPGDS) with IC50 value of 0.7nM [1].Prostaglandin D2 (PGD2) is a mediator of allergy and inflammation. |
![]() DGAT-1 inhibitor |
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A3363-200 | ApexBio | 200 mg | EUR 3208.8 |
Description: diacylglycerol acyltransferase (DGAT1) inhibitor |
![]() DGAT-1 inhibitor |
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A3363-25 | ApexBio | 25 mg | EUR 454.8 |
Description: diacylglycerol acyltransferase (DGAT1) inhibitor |
![]() DGAT-1 inhibitor |
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A3363-5 | ApexBio | 5 mg | EUR 157.2 |
Description: diacylglycerol acyltransferase (DGAT1) inhibitor |
![]() HPGDS inhibitor 1 |
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HY-10439 | MedChemExpress | 5mg | EUR 391.2 |
![]() PI3Kγ inhibitor 1 |
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HY-10549 | MedChemExpress | 50mg | EUR 2539.2 |
![]() LRRK2 inhibitor 1 |
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HY-111493 | MedChemExpress | 50mg | EUR 3159.6 |
![]() MAT2A inhibitor 1 |
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HY-112131 | MedChemExpress | 10mg | EUR 1093.2 |
![]() SIRT5 inhibitor 1 |
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HY-112634 | MedChemExpress | 10mM/1mL | EUR 1184.4 |
![]() PI3kδ inhibitor 1 |
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HY-15288 | MedChemExpress | 5mg | EUR 652.8 |
![]() Tubulin inhibitor 1 |
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HY-112607 | MedChemExpress | 50mg | EUR 2332.8 |
![]() YAP/TAZ inhibitor-1 |
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HY-111429 | MedChemExpress | 10mg | EUR 817.2 |
![]() Arginase inhibitor 1 |
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B1009-10 | ApexBio | 10 mg | EUR 970.8 |
Description: Arginase inhibitor 1 is a novel and potent small molecule inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively. |
![]() Arginase inhibitor 1 |
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B1009-100 | ApexBio | 100 mg | EUR 5706 |
Description: Arginase inhibitor 1 is a novel and potent small molecule inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively. |
![]() Arginase inhibitor 1 |
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B1009-5 | ApexBio | 5 mg | EUR 582 |
Description: Arginase inhibitor 1 is a novel and potent small molecule inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively. |
![]() Arginase inhibitor 1 |
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B1009-50 | ApexBio | 50 mg | EUR 3534 |
Description: Arginase inhibitor 1 is a novel and potent small molecule inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively. |
![]() Thrombin inhibitor 1 |
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HY-U00370 | MedChemExpress | 1mg | EUR 2804.4 |
![]() Arginase inhibitor 1 |
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HY-15775 | MedChemExpress | 50mg | EUR 2704.8 |
![]() Cathepsin Inhibitor 1 |
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B2084-100 | ApexBio | 100 mg | EUR 1394.4 |
Description: pIC50: 7.9, 6.7, 6.0, 5.5 and 5.2 for Cathepsin (L, L2, S, K, B), respectively. |
![]() Cathepsin Inhibitor 1 |
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B2084-5 | ApexBio | 5 mg | EUR 224.4 |
Description: pIC50: 7.9, 6.7, 6.0, 5.5 and 5.2 for Cathepsin (L, L2, S, K, B), respectively. |
![]() Cathepsin Inhibitor 1 |
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B2084-S | ApexBio | Evaluation Sample | EUR 97.2 |
Description: pIC50: 7.9, 6.7, 6.0, 5.5 and 5.2 for Cathepsin (L, L2, S, K, B), respectively. |
![]() Ribunuclease Inhibitor / RNase Inhibitor |
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105-310 | GeneOn | 2000 u | EUR 91.2 |
![]() Ribunuclease Inhibitor / RNase Inhibitor |
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105-350 | GeneOn | 10000 u | EUR 284.4 |
![]() B-Raf inhibitor 1 |
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B1172-10 | ApexBio | 10 mg | EUR 338.4 |
Description: B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively. |
![]() B-Raf inhibitor 1 |
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B1172-100 | ApexBio | 100 mg | EUR 2245.2 |
Description: B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively. |
![]() B-Raf inhibitor 1 |
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B1172-5 | ApexBio | 5 mg | EUR 234 |
Description: B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 uM and 2 nM for A375 proliferation and A375 p-ERK respectively. |